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Article

Analysis of promoter methylation, polymorphism and expression profile of cytotoxic T-lymphocyte-associated antigen-4 in patients with gastric cancer.

Journal of gastrointestinal and liver diseases : JGLD - 1 Sept 2014

Kordi-Tamandani Dor Mohammad, Davani Shahrbbanou Karimi, Baranzehi Taybeh, Hemati Simin

Abstract excerpt

BACKGROUND AND AIM: Cytotoxic T lymphocyte-associated antigen-4 (CTLA4) is a crucial immune-checkpoint receptor regulating T-cell activation. The current study was carried out to evaluate the function of CTLA4 gene in patients with gastric cancer. METHODS: The methylation of CTLA4 gene promoter was evaluated by methylation-specific polymerase chain reaction (MSP) technique using 85 paraffin-embedded gastric...

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Source

Identifiers

PMID: 25267951
DOI: 10.15403/jgld.2014.1121.233.dmkt

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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