Article
CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2006
Chang Moon-Sung, Uozaki Hiroshi, Chong Ja-Mun, Ushiku Tetsuo, Sakuma Kazuya, Ishikawa Shunpei, Hino Rumi, Barua Rita Rani, Iwasaki Yoshiaki, Arai Kuniyoshi, Fujii Hideki, Nagai Hideo, Fukayama Masashi
Abstract excerpt
PURPOSE: EBV-associated gastric carcinoma shows global CpG island methylation of the promoter region of various cancer-related genes. To further clarify the significance of CpG island methylator phenotype (CIMP) status in gastric carcinoma, we investigated methylation profile and clinicopathologic features including overall survival in four subgroups defined by EBV infection and CIMP status: EBV-associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
