Article
Impact of CYP2C19 polymorphism on clinical outcome following coronary stenting is more important in non-diabetic than diabetic patients.
Thrombosis research - 1 Jul 2014
Mizobe Michio, Hokimoto Seiji, Akasaka Tomonori, Arima Yuichiro, Kaikita Koichi, Morita Kazunori, Miyazaki Hiroko, Oniki Kentaro, Nakagawa Kazuko, Ogawa Hisao
Abstract excerpt
OBJECTIVE: The aim of this study was to examine the impact of CYP2C19 genotype on clinical outcome in coronary artery disease (CAD) patients with or without diabetes mellitus (DM). METHODS: CYP2C19 polymorphism and DM are associated with increased risk of cardiovascular events during antiplatelet therapy following stent implantation. Platelet reactivity during clopidogrel therapy and CYP2C19 polymorphism were...
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