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Article

Planar cell polarity aligns osteoblast division in response to substrate strain.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Mar 2015

Galea Gabriel L, Meakin Lee B, Savery Dawn, Taipaleenmaki Hanna, Delisser Peter, Stein Gary S, Copp Andrew J, van Wijnen Andre J, Lanyon Lance E, Price Joanna S

Abstract excerpt

Exposure of bone to dynamic strain increases the rate of division of osteoblasts and also influences the directional organization of the cellular and molecular structure of the bone tissue that they produce. Here, we report that brief exposure to dynamic substrate strain (sufficient to rapidly st...

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Identifiers

PMID: 25264362
DOI: 10.1002/jbmr.2377
PMCID: PMC4333081

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25264362-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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