Article
Are serotonin 3A and 3B receptor genes associated with suicidal behavior in schizophrenia subjects?
Neuroscience letters - 11 Feb 2011
Souza Renan P, De Luca Vincenzo, Manchia Mirko, Kennedy James L
Abstract excerpt
Suicide is a major contributor to the morbidity and mortality of schizophrenia, accounting for approximately 10% of deaths in these patients. Genetic factors have been reported to modulate the risk for suicide, although the precise mechanism and magnitude of the genetic contribution are unknown. Further, suicide attempters present abnormalities in the serotonergic system. We evaluated whether genetic variants in...
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