Article
Association study of BDNF and DRD3 genes with alcohol use disorder in Schizophrenia.
Neuroscience letters - 3 Apr 2018
Zai Clement C, Manchia Mirko, Zai Gwyneth C, Woo Julia, Tiwari Arun K, de Luca Vincenzo, Kennedy James L
Abstract excerpt
Alcohol use disorder (AUD) is a leading risk factor of disease burden in the world. It is also commonly comorbid with over 20% of schizophrenia patients. The brain-derived neurotrophic factor (BDNF) and dopamine D3 receptor (DRD3) have been implicated in alcohol drinking behaviour. Previous genetic studies of the BDNF and DRD3 genes produced mixed findings; however, only one study investigated two BDNF genetic...
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