Article
Parent of origin effect and differential allelic expression of BDNF Val66Met in suicidal behaviour.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Feb 2011
de Luca Vincenzo, Souza Renan P, Zai Clement C, Panariello Fabio, Javaid Naima, Strauss John, Kennedy James L, Tallerico Teresa, Wong Albert H
Abstract excerpt
OBJECTIVES: Brain-derived neurotrophic factor (BDNF) plays an important role in the pathophysiology of mood disorders and may also be involved in suicidal behaviour since BDNF levels are decreased in brain and plasma of suicide victims. Because the differential allelic expression of Val66Met BDNF gene on suicidal behaviour has not been investigated, we analyzed the parent-of-origin effect (POE) in suicide...
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