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Article

Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.

Oncotarget - 30 Sept 2014

Ress Anna Lena, Stiegelbauer Verena, Schwarzenbacher Daniela, Deutsch Alexander, Perakis Samantha, Ling Hui, Ivan Cristina, Calin George Adrian, Rinner Beate, Gerger Armin, Pichler Martin

Abstract excerpt

The putative tumor suppressor gene spinophilin has been involved in cancer progression in several types of cancer. In this study, we explored the prognostic value of spinophilin expression in 162 colon adenocarcinoma patients. In addition, we generated stably expressing spinophilin-directed shRNA CRC cell lines and studied the influence of spinophilin expression on cellular phenotypes and molecular interactions....

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Identifiers

PMID: 25261368
DOI: 10.18632/oncotarget.2329
PMCID: PMC4226699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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