Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancer

8 Nov 2022

Abstract excerpt

Tumor stem cells play a pivotal role in carcinogenesis and metastatic spread in colorectal cancer (CRC). Olfactomedin 4 (OLFM4) is co-expressed with the established stem cell marker leucine-rich repeat-containing G protein-coupled receptor 5 at the bottom of intestinal crypts and has been suggested as a surrogate for cancer stemness and a biomarker in gastrointestinal tumors associated with prognosis. Therefore,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Medicinal Plant Pharmacodynamics Research
Share to Metastasis and carcinoma case studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36349502
DOI: 10.1002/cjp2.300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancerPMID 36349502Read ↗

Paneth-like cells produced from OLFM4+ stem cells support OLFM4+ stem cell growth in advanced colorectal cancerSemantic proximity Read ↗

Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal CancerSemantic proximity Read ↗

Identification, isolation and characterization of human LGR5-positive colon adenoma cellsSemantic proximity Read ↗

OLFM4 Enhances STAT3 Activation and Promotes Tumor Progression by Inhibiting GRIM19 Expression in Human Hepatocellular CarcinomaSemantic proximity Read ↗

Identification, Isolation, and Characterization of Human LGR5-positive Colon Adenoma CellsSemantic proximity Read ↗

Wnt5a suppresses colorectal cancer progression via TGF-β/NOTUM/OLFM4 axis in patient-derived organoidsSemantic proximity Read ↗

Plasma levels of OLFM 4 in normals and patients with gastrointestinal cancerSemantic proximity Read ↗

Defining the role of Lgr5+ stem cells in colorectal cancer: from basic research to clinical applicationsSemantic proximity Read ↗

Specific overexpression of OLFM4<sup>GW112/hGC−1</sup> mRNA in colon, breast and lung cancer tissues detected using quantitative analysisSemantic proximity Read ↗

SFRP4 expression correlates with epithelial mesenchymal transition-linked genes and poor overall survival in colon cancer patientsSemantic proximity Read ↗

Olfactomedin 4 deletion induces colon adenocarcinoma in ApcMin/+ mice.Semantic proximity Read ↗

In situ validation of an intestinal stem cell signature in colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.