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Article

Multifaceted Interpretation of Colon Cancer Stem Cells.

International journal of molecular sciences - 5 Jul 2017

Hatano Yuichiro, Fukuda Shinya, Hisamatsu Kenji, Hirata Akihiro, Hara Akira, Tomita Hiroyuki

Abstract excerpt

Colon cancer is one of the leading causes of cancer-related deaths worldwide, despite recent advances in clinical oncology. Accumulating evidence sheds light on the existence of cancer stem cells and their role in conferring therapeutic resistance. Cancer stem cells are a minor fraction of cancer cells, which enable tumor heterogeneity and initiate tumor formation. In addition, these cells are resistant to...

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Identifiers

PMID: 28678194
DOI: 10.3390/ijms18071446
PMCID: PMC5535937

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