Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anterograde Activin signaling regulates postsynaptic membrane potential and GluRIIA/B abundance at the Drosophila neuromuscular junction.

PloS one - 1 Jan 2014

Kim Myung-Jun, O'Connor Michael B

Abstract excerpt

Members of the TGF-β superfamily play numerous roles in nervous system development and function. In Drosophila, retrograde BMP signaling at the neuromuscular junction (NMJ) is required presynaptically for proper synapse growth and neurotransmitter release. In this study, we analyzed whether the Activin branch of the TGF-β superfamily also contributes to NMJ development and function. We find that elimination of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activins
Share to Drosophila Proteins
Share to Ligands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuromuscular Junction

Share to Protein Transport

Share to Receptors, Glutamate

Share to Transforming Growth Factor beta

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25255438
DOI: 10.1371/journal.pone.0107443
PMCID: PMC4177838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anterograde Activin signaling regulates postsynaptic membrane potential and GluRIIA/B abundance at the Drosophila neuromuscular junction.PMID 25255438Read ↗

The BMP homolog Gbb provides a retrograde signal that regulates synaptic growth at the Drosophila neuromuscular junction.Semantic proximity Read ↗

TGF-beta signals regulate axonal development through distinct Smad-independent mechanisms.Semantic proximity Read ↗

BMP signaling modulates the probability of neurotransmitter release and readily releasable pools in Drosophila neuromuscular junction synapses.Semantic proximity Read ↗

The Crossroads of Synaptic Growth Signaling, Membrane Traffic and Neurological Disease: Insights from <i>Drosophila</i>Semantic proximity Read ↗

The divergent TGF-beta ligand Dawdle utilizes an activin pathway to influence axon guidance in Drosophila.Semantic proximity Read ↗

Motoneuron Wnts regulate neuromuscular junction development.Semantic proximity Read ↗

Synaptic homeostasis is consolidated by the cell fate gene gooseberry, a Drosophila pax3/7 homolog.Semantic proximity Read ↗

The Drosophila BMP type II receptor Wishful Thinking regulates neuromuscular synapse morphology and function.Semantic proximity Read ↗

MAN1 Restricts BMP Signaling During Synaptic Growth in Drosophila.Semantic proximity Read ↗

Retrograde signaling by Syt 4 induces presynaptic release and synapse-specific growth.Semantic proximity Read ↗

dCIP4 (Drosophila Cdc42-interacting protein 4) restrains synaptic growth by inhibiting the secretion of the retrograde Glass bottom boat signal.Semantic proximity Read ↗

Synaptic patterning by morphogen signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.