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Article

Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL.

Neurobiology of disease - 1 Jan 2015

Liu Xiao-Yun, Gonzalez-Toledo Maria E, Fagan Austin, Duan Wei-Ming, Liu Yanying, Zhang Siyuan, Li Bin, Piao Chun-Shu, Nelson Lila, Zhao Li-Ru

Abstract excerpt

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a Notch3 dominant mutation-induced cerebral small vascular disease, is characterized by progressive degeneration of vascular smooth muscle cells (vSMCs) of small arteries in the brain, leading to...

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Source

Identifiers

PMID: 25251607
DOI: 10.1016/j.nbd.2014.09.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25251607-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL.PMID 25251607Read ↗

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Selective vulnerability of cerebral vasculature to <i>NOTCH3</i> variants in small vessel disease and rescue by phosphodiesterase-5 inhibitorSemantic proximity Read ↗

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