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Article

Smoking accelerates aging of the small airway epithelium

23 Sept 2014

Abstract excerpt

BACKGROUND: Aging involves multiple biologically complex processes characterized by a decline in cellular homeostasis over time leading to a loss and impairment of physiological integrity and function. Specific cellular hallmarks of aging include abnormal gene expression patterns, shortened telomeres and associated biological dysfunction. Like all organs, the lung demonstrates both physiological and structural...

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PMID: 25248511
DOI: 10.1186/s12931-014-0094-1

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