Article
Differential activation of cord blood and peripheral blood natural killer cells by cytokines.
Cytotherapy - 1 Jan 2015
Alnabhan Rehab, Madrigal Alejandro, Saudemont Aurore
Abstract excerpt
BACKGROUND AIMS: Natural killer (NK) cells play important roles in the clearance of infection and transformed cells. Cord blood (CB) is currently used as a source of hematopoietic stem cells for transplantation and is a potential source of NK cells for immunotherapy. We previously showed that CB NK cells are immature and less cytotoxic as compared with peripheral blood (PB) NK cells. We aimed to identify which...
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