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Article

Genetic and structural analysis of Merkel cell polyomavirus large T antigen from diverse biological samples.

Intervirology - 1 Jan 2014

Freze Baez Camila, Cirauqui Diaz Nuria, Baeta Cavalcanti Silvia Maria, Brandão Varella Rafael

Abstract excerpt

Merkel cell polyomavirus (MCPyV) large T antigen (LT-ag) is frequently found truncated in Merkel cell carcinomas (MCC) and it is considered a major tumor-specific signature. Nonetheless, the biological role of LT-ag nontruncated mutations is largely unknown. In this study, MCPyV LT-ag second exon from 11 non-MCC oral samples and NCBI sequences derived from different anatomical sites were studied from the genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25247791
DOI: 10.1159/000363241

Genes

MCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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