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Merkel cell polyomavirus and non‐Merkel cell carcinomas: guilty or circumstantial evidence?

28 Jan 2020

Abstract excerpt

Merkel cell polyomavirus (MCPyV) is the major causative factor of the rare but aggressive cancer, Merkel cell carcinoma (MCC). Two characteristics of MCPyV-positive MCCs are integration of the viral genome and expression of a truncated version of one of its oncogenic proteins, namely large T antigen. The strong association of MCPyV with MCC development has incited researchers to further investigate a possible...

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PMID: 31990105
DOI: 10.1111/apm.13019

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