Article
Genetic variability and integration of Merkel cell polyomavirus in Merkel cell carcinoma.
Virology - 10 May 2012
Martel-Jantin C, Filippone C, Cassar O, Peter M, Tomasic G, Vielh P, Brière J, Petrella T, Aubriot-Lorton M H, Mortier L, Jouvion G, Sastre-Garau X, Robert C, Gessain A
Abstract excerpt
Merkel cell polyomavirus (MCPyV) is associated to Merkel cell carcinoma (MCC). We studied 113 MCC tumoral skin lesions originating from 97 patients. MCPyV detection was higher in fresh-frozen (FF) biopsies (94%) than in formalin-fixed paraffin-embedded biopsies (39-47%). Mean viral load in FF tum...
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