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Article

DiffVar: a new method for detecting differential variability with application to methylation in cancer and aging.

Genome biology - 23 Sept 2014

Phipson Belinda, Oshlack Alicia

Abstract excerpt

Methylation of DNA is known to be essential to development and dramatically altered in cancers. The Illumina HumanMethylation450 BeadChip has been used extensively as a cost-effective way to profile nearly half a million CpG sites across the human genome. Here we present DiffVar, a novel method to test for differential variability between sample groups. DiffVar employs an empirical Bayes model framework that can...

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Identifiers

PMID: 25245051
DOI: 10.1186/s13059-014-0465-4
PMCID: PMC4210618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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