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Assessment of mitochondrial DNA mutations in Chinese family with essential hypertension.

Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 May 2016

Sun Guo-Ju, He Fei, Yao Hai-Mu, Han Zhan-Ying, Lu Wen-Jie, Chen Xiao-Jie, Wang Zheng-Bin, Qiu Chun-Guang

Abstract excerpt

Mitochondrial DNA (MtDNA) mutations played an important role in the development of essential hypertension. Mitochondrial tRNA point mutations, caused the failure in tRNA metabolism, responsible for the pathogenesis of this complex disease. In this study, we evaluated the possible role of the 4329C >G mutation in the clinical expression of hypertension in a Chinese family. Analysis of the complete mtDNA sequence...

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Identifiers

PMID: 25242182
DOI: 10.3109/19401736.2014.961148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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