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Article

Alternative splicing impairs soluble guanylyl cyclase function in aortic aneurysm.

American journal of physiology. Heart and circulatory physiology - 1 Dec 2014

Martin Emil, Golunski Eva, Laing Susan T, Estrera Anthony L, Sharina Iraida G

Abstract excerpt

Nitric oxide (NO) receptor soluble guanylyl cyclase (sGC) is a key regulator of several important vascular functions and is important for maintaining cardiovascular homeostasis and vascular plasticity. Diminished sGC expression and function contributes to pathogenesis of several cardiovascular di...

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Identifiers

PMID: 25239802
DOI: 10.1152/ajpheart.00222.2014
PMCID: PMC4255009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25239802-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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