Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diverging alternative splicing fingerprints in the transforming growth factor-β signaling pathway identified in thoracic aortic aneurysms.

Molecular medicine (Cambridge, Mass.) - 1 Jan 2011

Kurtovic Sanela, Paloschi Valentina, Folkersen Lasse, Gottfries Johan, Franco-Cereceda Anders, Eriksson Per

Abstract excerpt

Impaired regulation of the transforming growth factor-β (TGFβ) signaling pathway has been linked to thoracic aortic aneurysm (TAA). Previous work has indicated that differential splicing is a common phenomenon, potentially influencing the function of proteins. In the present study we investigated the occurrence of differential splicing in the TGFβ pathway associated with TAA in patients with bicuspid aortic valve...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Aorta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aortic Aneurysm, Thoracic

Share to Dilatation, Pathologic

Share to Mitral Valve

Share to Principal Component Analysis

Share to Transforming Growth Factor beta

Source

Open in PubMed Open full text

Identifiers

PMID: 21448509
DOI: 10.2119/molmed.2011.00018
PMCID: PMC3146609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Diverging alternative splicing fingerprints in the transforming growth factor-β signaling pathway identified in thoracic aortic aneurysms.PMID 21448509Read ↗

Impaired splicing of fibronectin is associated with thoracic aortic aneurysm formation in patients with bicuspid aortic valve.Semantic proximity Read ↗

A Combined Proteomic and Transcriptomic Approach Shows Diverging Molecular Mechanisms in Thoracic Aortic Aneurysm Development in Patients with Tricuspid- And Bicuspid Aortic ValveSemantic proximity Read ↗

Distinct transcriptomic patterns in bicuspid aortic valve aortopathy suggest a unique mechanism of ascending aortic aneurysm progressionSemantic proximity Read ↗

The mir‐200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valvesSemantic proximity Read ↗

Focus on the unique mechanisms involved in thoracic aortic aneurysm formation in bicuspid aortic valve versus tricuspid aortic valve patients: clinical implications of a pilot study.Semantic proximity Read ↗

Altered Patterns of Gene Expression Specific to Thoracic Aortic Aneurysms: Microarray Analysis of Surgically Resected SpecimensSemantic proximity Read ↗

Alternative splicing impairs soluble guanylyl cyclase function in aortic aneurysm.Semantic proximity Read ↗

Alternative splicing is an efficient mechanism for the generation of protein diversity: contractile protein genes as a model system.Semantic proximity Read ↗

A Preliminary microRNA Analysis of non Syndromic Thoracic Aortic AneurysmsSemantic proximity Read ↗

Alternative splicing of α1 and β1 sGC genes is altered in aortic diseaseSemantic proximity Read ↗

Protective effects of angiotensin-converting enzyme I/I and matrix metalloproteinase-3 6A/6A polymorphisms on dilatative pathology within the ascending thoracic aorta.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.