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Article

Prothrombotic platelet phenotype in major depression: downregulation by antidepressant treatment.

Journal of affective disorders - 1 Apr 2014

Lopez-Vilchez Irene, Serra-Millas Montserrat, Navarro Victor, Rosa Hernandez M, Villalta Jaume, Diaz-Ricart Maribel, Gasto Cristobal, Escolar Gines, Galan Ana M

Abstract excerpt

BACKGROUND: Serotonergic mechanisms have been suggested as a link between major depression and cardiovascular risk. We investigated the existence of a prothrombotic condition in depressed patients and its possible modulation during treatment with a selective serotonin-reuptake inhibitor (SSRI). METHODS: Modifications in a series of biomarkers of platelet and coagulation activation were evaluated in blood from 19...

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Identifiers

PMID: 24679387
DOI: 10.1016/j.jad.2014.02.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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