Article
Update on different aspects of HCV variability: focus on NS5B polymerase.
BMC infectious diseases - 1 Jan 2014
Marascio Nadia, Torti Carlo, Liberto Maria, Focà Alfredo
Abstract excerpt
The study of hepatitis C virus (HCV) genotypes/subtypes, quasispecies and recombinants obtained by virus genome sequencing are important for epidemiological studies, to trace the source of infection, for development of new direct acting antivirals (DAAs) therapy and for understanding antiviral selection pressures. The HCV NS5B gene encodes a polymerase, which is responsible for virus replication and is a...
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