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Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B

28 Sept 2010

Abstract excerpt

More than 20 years after the identification of the hepatitis C virus (HCV) as a novel human pathogen, the only approved treatment remains a combination of pegylated interferon-α and ribavirin. This rather non-specific therapy is associated with severe side effects and by far not everyone benefits from treatment. Recently, progress has been made in the development of specifically targeted antiviral therapy for HCV...

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PMID: 21994615
DOI: 10.3390/v2102169

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