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Article

Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A

18 Sept 2014

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is driven by the accumulation of somatic mutations, epigenetic modifications and changes in the micro-environment. New approaches to investigating disruptions of gene expression networks promise to uncover key regulators and pathways in carcinogenesis. We performed messenger RNA-sequencing in pancreatic normal (n = 10) and tumor (n = 8) derived tissue samples, as well as in...

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Share to Epigenetics and DNA Methylation
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PMID: 25233928
DOI: 10.1093/carcin/bgu193

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