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Article

Drivers of Gene Expression Dysregulation in Pancreatic Cancer.

Trends in cancer - 1 Jul 2021

Venkat Swati, Alahmari Abdulrahman A, Feigin Michael E

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease with a poor prognosis. The functional consequences of common genetic aberrations and their roles in treatment strategies have been extensively reviewed. In addition to these genomic aberrations, consideration of non-genetic drivers of altered oncogene expression is essential to account for the diversity in PDAC phenotypes. In this review we...

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Topics

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Share to Carcinoma, Pancreatic Ductal
Share to Cell Line, Tumor
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genetic Heterogeneity

Share to Pancreatic Neoplasms

Share to Tumor Microenvironment

Share to Xenograft Model Antitumor Assays

Source

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Identifiers

PMID: 33618999
DOI: 10.1016/j.trecan.2021.01.008
PMCID: PMC8217125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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