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Prognostic relevance of molecular subtypes and master regulators in pancreatic ductal adenocarcinoma

12 Aug 2016

Abstract excerpt

BACKGROUND: Pancreatic cancer is poorly characterized at genetic and non-genetic levels. The current study evaluates in a large cohort of patients the prognostic relevance of molecular subtypes and key transcription factors in pancreatic ductal adenocarcinoma (PDAC). METHODS: We performed gene expression analysis of whole-tumor tissue obtained from 118 surgically resected PDAC and 13 histologically normal...

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PMID: 27520560
DOI: 10.1186/s12885-016-2540-6

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