Article
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.
The Journal of allergy and clinical immunology - 1 Feb 2010
Li Xingnan, Howard Timothy D, Zheng Siqun L, Haselkorn Tmirah, Peters Stephen P, Meyers Deborah A, Bleecker Eugene R
Abstract excerpt
BACKGROUND: Asthma is a heterogeneous disease that is caused by the interaction of genetic susceptibility with environmental influences. Genome-wide association studies (GWASs) represent a powerful approach to investigate the association of DNA variants with disease susceptibility. To date, few GWASs for asthma have been reported. OBJECTIVES: A GWAS was performed on a population of patients with severe or...
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