Article
Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma.
Human heredity - 1 Jan 2011
Murk William, Walsh Kyle, Hsu Ling-I, Zhao Linlu, Bracken Michael B, Dewan Andrew T
Abstract excerpt
OBJECTIVES: Asthma is a childhood disease that is strongly influenced by genetic factors. We sought to replicate an association between single nucleotide polymorphisms (SNPs) of the top-ranked candidate genes and childhood atopic asthma in Perinatal Risk of Asthma in Infants of Asthmatic Mothers (PRAM) study subjects. METHODS: Using data from a systematic literature search and an exploratory genome-wide...
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