Article
Polymorphisms of RAD50, IL33 and IL1RL1 are associated with atopic asthma in Chinese population.
Tissue antigens - 1 Dec 2015
Chen J, Zhang J, Hu H, Jin Y, Xue M
Abstract excerpt
Genetic architecture of asthma remains obscure. This study aimed to investigate whether the genetic polymorphisms of CDHR3 (rs6967330), GSDMB (rs2305480), IL33 rs928413, RAD50 (rs6871536) and IL1RL1 (rs1558641) are associated with the development of atopic asthma in Chinese population. Genotype and allele frequencies were compared between 516 patients and 552 controls by Chi-square test. Patients were found to...