Article
Lack of association of the NPAS2 gene Ala394Thr polymorphism (rs2305160:G>A) with risk of chronic lymphocytic leukemia.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Rana Sobia, Shahid Adeela, Ullah Hafeez, Mahmood Saqib
Abstract excerpt
BACKGROUND: NPAS2 is a product of the circadian clock gene. It acts as a putative tumor suppressor by playing an important role in DNA damage responses, cell cycle control and apoptosis. Chronic lymphocytic leukemia (CLL) appears to be an apoptosis related disorder and alteration in the NPAS2 gen...
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