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Article

The role of MTNR1B polymorphism on circadian rhythm-related cancer: A UK Biobank cohort study.

International journal of cancer - 15 Sept 2022

Wu Jiafei, Tan Xiao

Abstract excerpt

A common G risk allele in the melatonin receptor 1B (MTNR1B, rs10830963) gene has been associated with altered melatonin signaling and secretion. Given that melatonin possesses anticancerogenic properties, we hypothesized that breast and prostate cancer risks vary by rs10830963 genotype. A total of 216 702 participants from the UK Biobank without cancer at baseline (aged 56.4 ± 8.0 years, 50.79% female) were...

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Identifiers

PMID: 35467761
DOI: 10.1002/ijc.34047
PMCID: PMC9545001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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