Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in key genes associated with statin therapy in the Azores Islands (Portugal) healthy population.

Annals of human biology - 1 Jan 2015

Melo Mafalda S, Balanco Leticia, Branco Claudia C, Mota-Vieira Luisa

Abstract excerpt

BACKGROUND: Inter-individual variation in response to statins (efficacy and toxicity) has been described and may be due to polymorphisms implicated in drug pharmacokinetics or pharmacodynamics. AIM: This study investigates clinically relevant pharmacogenes underlying statin response in 170 health...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to APOE gene
Share to CETP gene
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HMGCR gene

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25224634
DOI: 10.3109/03014460.2014.955056

Genes

APOE
CETP
HMGCR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25224634-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in key genes associated with statin therapy in the Azores Islands (Portugal) healthy population.PMID 25224634Read ↗

Pharmacogenetics of statins treatment: Efficacy and safetySemantic proximity Read ↗

Impact of SLCO1B1 and ABCB1 variants on statin efficacy and toxicity in a Tunisian population.Semantic proximity Read ↗

Pharmacogenomic insights into atorvastatin and rosuvastatin adverse effects: a prospective observational study in the UAE's multiethnic population.Semantic proximity Read ↗

Comparative Analysis of Atorvastatin and Rosuvastatin Side Events and Risk Factors in the UAE Multiethnic Population: Focus on Pharmacogenomic VariantsSemantic proximity Read ↗

Pharmacogenomic variants affecting efficacy and toxicity of statins in a south Asian population from Sri Lanka.Semantic proximity Read ↗

Clinical implications of pharmacogenetic variation on the effects of statins.Semantic proximity Read ↗

Personalised medicine in hypercholesterolaemia: the role of pharmacogenetics in statin therapy.Semantic proximity Read ↗

SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group.Semantic proximity Read ↗

Genetic determinants of lipid-lowering response to atorvastatin therapy in an Indian population.Semantic proximity Read ↗

Prevalence of protective haplotypes of the SLCO1B1 gene for statin transport in Mexican populations.Semantic proximity Read ↗

Statins personalized.Semantic proximity Read ↗

Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.