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Article

Genetic variation in key genes associated with statin therapy in the Azores Islands (Portugal) healthy population.

Annals of human biology - 1 Jan 2015

Melo Mafalda S, Balanco Leticia, Branco Claudia C, Mota-Vieira Luisa

Abstract excerpt

BACKGROUND: Inter-individual variation in response to statins (efficacy and toxicity) has been described and may be due to polymorphisms implicated in drug pharmacokinetics or pharmacodynamics. AIM: This study investigates clinically relevant pharmacogenes underlying statin response in 170 healthy Azoreans. METHODS: Eight SNPs in candidate genes-HMGCR (rs3846662, rs17238540, rs17244841), CETP (rs708272), APOE...

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Source

Identifiers

PMID: 25224634
DOI: 10.3109/03014460.2014.955056

Genes

APOE
CETP
HMGCR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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