Article
Prevalence of protective haplotypes of the SLCO1B1 gene for statin transport in Mexican populations.
Personalized medicine - 1 Sept 2021
Favela-Mendoza Alma Faviola, Rodríguez-Rodríguez Brenda Guadalupe, Rojas-Prado Eduardo, Chávez-Arreguin Mariana, Aguilar-Velázquez José Alonso, Martínez-Cortés Gabriela, Rangel-Villalobos Héctor
Abstract excerpt
Aim: To evaluate the genetic distribution of the rs4149056 and rs2306283 variants in the SLCO1B1 gene in Mexican Mestizo (admixed) and Native American groups. Materials & methods: We recruited 360 volunteers who were qPCR-genotyped with TaqMan probes. Results: Allele and genotype frequencies are reported. Among the expected rs4149056-rs2306283 haplotypes, T-A (42.35-58.47%) was the most prevalent which relates to...
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