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Article

MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy.

Molecular psychiatry - 1 Jan 2014

Reif A, Richter J, Straube B, Höfler M, Lueken U, Gloster A T, Weber H, Domschke K, Fehm L, Ströhle A, Jansen A, Gerlach A, Pyka M, Reinhardt I, Konrad C, Wittmann A, Pfleiderer B, Alpers G W, Pauli P, Lang T, Arolt V, Wittchen H-U, Hamm A, Kircher T, Deckert J

Abstract excerpt

Panic disorder with agoraphobia (PD/AG) is a prevalent mental disorder featuring a substantial complex genetic component. At present, only a few established risk genes exist. Among these, the gene encoding monoamine oxidase A (MAOA) is noteworthy given that genetic variation has been demonstrated to influence gene expression and monoamine levels. Long alleles of the MAOA-uVNTR promoter polymorphism are associated...

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Identifiers

PMID: 23319006
DOI: 10.1038/mp.2012.172

Genes

MAOA
CS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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