GWAS of 972 autologous stem cell recipients with multiple myeloma identifies 11 genetic variants associated with chemotherapy-induced oral mucositis.

doi:10.1007/s00520-014-2406-x

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Article

GWAS of 972 autologous stem cell recipients with multiple myeloma identifies 11 genetic variants associated with chemotherapy-induced oral mucositis.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer - 1 Mar 2015

Coleman Elizabeth Ann, Lee Jeannette Y, Erickson Stephen W, Goodwin Julia A, Sanathkumar Naveen, Raj Vinay R, Zhou Daohong, McKelvey Kent D, Apewokin Senu, Stephens Owen, Enderlin Carol A, Vangsted Annette Juul, Reed Patty J, Anaissie Elias J

Abstract excerpt

PURPOSE: High-dose chemotherapy and autologous stem cell transplant (ASCT) to treat multiple myeloma (MM) and other cancers carries the risk of oral mucositis (OM) with sequelae including impaired nutritional and fluid intake, pain, and infectious complications. As a result of these problems, cancer treatment may have to be interrupted or delayed. In this study, we looked beyond OM's known risk factors of renal...

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Identifiers

PMID: 25218607
DOI: 10.1007/s00520-014-2406-x
PMCID: PMC4371856

Genes

DMRTA1
FBN2
JPH3

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