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Article

ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.

Human molecular genetics - 1 Feb 2015

Morozko Eva L, Nishio Ayako, Ingham Neil J, Chandra Rashmi, Fitzgerald Tracy, Martelletti Elisa, Borck Guntram, Wilson Elizabeth, Riordan Gavin P, Wangemann Philine, Forge Andrew, Steel Karen P, Liddle Rodger A, Friedman Thomas B, Belyantseva Inna A

Abstract excerpt

In the mammalian inner ear, bicellular and tricellular tight junctions (tTJs) seal the paracellular space between epithelial cells. Tricellulin and immunoglobulin-like (Ig-like) domain containing receptor 1 (ILDR1, also referred to as angulin-2) localize to tTJs of the sensory and non-sensory epi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25217574
DOI: 10.1093/hmg/ddu474
PMCID: PMC4291242

Genes

ILDR1
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25217574-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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