Article
Tricellulin is a tight-junction protein necessary for hearing.
American journal of human genetics - 1 Dec 2006
Riazuddin Saima, Ahmed Zubair M, Fanning Alan S, Lagziel Ayala, Kitajiri Shin-ichiro, Ramzan Khushnooda, Khan Shaheen N, Chattaraj Parna, Friedman Penelope L, Anderson James M, Belyantseva Inna A, Forge Andrew, Riazuddin Sheikh, Friedman Thomas B
Abstract excerpt
The inner ear has fluid-filled compartments of different ionic compositions, including the endolymphatic and perilymphatic spaces of the organ of Corti; the separation from one another by epithelial barriers is required for normal hearing. TRIC encodes tricellulin, a recently discovered tight-junction (TJ) protein that contributes to the structure and function of tricellular contacts of neighboring cells in many...
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