Article
[Clinical relevance of the K-ras oncogene in colorectal cancer: experience in a Mexican population].
Revista de gastroenterologia de Mexico - 1 Jan 2000
Cabrera-Mendoza F, Gainza-Lagunes S, Castañeda-Andrade I, Castro-Zárate A
Abstract excerpt
BACKGROUND: Colorectal cancer is frequent in the developed countries, with a cancer-specific mortality rate of 33%. Different biomarkers are associated with overall survival and the prediction of monoclonal treatment effectiveness. The presence of mutations in the K-ras oncogene alters the response to target therapy with cetuximab and could be an independent prognostic factor. AIMS: To analyze the difference in...
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