Article
Are high initial CEA and CA 19-9 levels associated with the presence of K-ras mutation in patients with metastatic colorectal cancer?
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2013
Selcukbiricik Fatih, Bilici Ahmet, Tural Deniz, Erdamar Sibel, Soyluk Ozlem, Buyukunal Evin, Demirelli Fuat, Serdengecti Suheyla
Abstract excerpt
In certain cell culture studies, significant CEA expression was observed in K-ras mutant cells. However, the relationship between high CEA levels and K-ras status has not been sufficiently investigated. In the present study, we aimed to determine the prognostic role of initial CEA and CA 19-9 values in metastatic colorectal cancer patients according to the status of K-ras. Between 2000 and 2010, a total of 215...
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