Article
Causal variation in yeast sporulation tends to reside in a pathway bottleneck.
PLoS genetics - 1 Sept 2014
Lorenz Kim, Cohen Barak A
Abstract excerpt
There has been extensive debate over whether certain classes of genes are more likely than others to contain the causal variants responsible for phenotypic differences in complex traits between individuals. One hypothesis states that input/output genes positioned in signal transduction bottleneck...
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