Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish.

PloS one - 1 Jan 2012

Goodale Britton C, La Du Jane K, Bisson William H, Janszen Derek B, Waters Katrina M, Tanguay Robert L

Abstract excerpt

The aryl hydrocarbon receptor (AHR) is well known for mediating the toxic effects of TCDD and has been a subject of intense research for over 30 years. Current investigations continue to uncover its endogenous and regulatory roles in a wide variety of cellular and molecular signaling processes. A zebrafish line with a mutation in ahr2 (ahr2(hu3335)), encoding the AHR paralogue responsible for mediating TCDD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Bone and Bones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to Isoxazoles

Share to Polychlorinated Dibenzodioxins

Share to Receptors, Aryl Hydrocarbon

Share to Thermodynamics

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22242167
DOI: 10.1371/journal.pone.0029346
PMCID: PMC3252317

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish.PMID 22242167Read ↗

RNA-Sequencing Analysis of TCDD-Induced Responses in Zebrafish Liver Reveals High Relatedness to In Vivo Mammalian Models and Conserved Biological PathwaysSemantic proximity Read ↗

Distinct roles of two zebrafish AHR repressors (AHRRa and AHRRb) in embryonic development and regulating the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.Semantic proximity Read ↗

Identifying TCDD-resistance genes via murine and rat comparative genomics and transcriptomicsSemantic proximity Read ↗

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.Semantic proximity Read ↗

Novel role of hnRNP-A2/B1 in modulating aryl hydrocarbon receptor ligand sensitivity.Semantic proximity Read ↗

Functional characterization and evolutionary history of two aryl hydrocarbon receptor isoforms (AhR1 and AhR2) from avian species.Semantic proximity Read ↗

Unexpected diversity of aryl hydrocarbon receptors in non-mammalian vertebrates: insights from comparative genomics.Semantic proximity Read ↗

Molecular Evolution of Aryl Hydrocarbon Receptor Signaling Pathway GenesSemantic proximity Read ↗

Exposure to the aryl hydrocarbon receptor agonist dioxin disrupts formation of the muscle, nerves, and vasculature in the developing jawSemantic proximity Read ↗

Understanding dioxin developmental toxicity using the zebrafish modelSemantic proximity Read ↗

Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor.Semantic proximity Read ↗

Zebrafish as Toxicological Model for Screening and Recapitulate Human DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.