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Article

PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis.

World journal of gastroenterology - 7 Sept 2014

Pelaez-Luna Mario, Robles-Diaz Guillermo, Canizales-Quinteros Samuel, Tusié-Luna Maria T

Abstract excerpt

AIM: To identify gene mutations in PRSS1 and SPINK1 in individuals with early onset idiopathic chronic or recurrent acute pancreatitis. METHODS: The cationic trypsinogen gene (PRSS1; exons 2 and 3) and the serine protease inhibitor Kazal 1 gene (SPINK1; exon 3) were selectively amplified and sequenced from blood samples of 19 patients admitted to the Pancreas Clinic at our institution with chronic pancreatitis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25206283
DOI: 10.3748/wjg.v20.i33.11788
PMCID: PMC4155369

Genes

SPINK1
PRSS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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