Article
Absence of PRSS1 mutations and association of SPINK1 trypsin inhibitor mutations in hereditary and non-hereditary chronic pancreatitis.
Gut - 1 May 2004
Chandak G R, Idris M M, Reddy D N, Mani K R, Bhaskar S, Rao G V, Singh L
Abstract excerpt
BACKGROUND AND AIMS: Mutations in the cationic trypsinogen (protease, serine, 1 (trypsin 1); PRSS1) gene are causally associated with recurrent acute and chronic pancreatitis. We investigated whether mutations in the PRSS1 gene are associated with hereditary and non-hereditary pancreatitis. As a modifier role has been proposed for trypsin inhibitor (serine protease inhibitor, Kazal type I; SPINK1) mutations, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.