Article
Genetic Analysis of Japanese Children With Acute Recurrent and Chronic Pancreatitis.
Journal of pediatric gastroenterology and nutrition - 1 Oct 2016
Saito Nobutomo, Suzuki Mitsuyoshi, Sakurai Yumiko, Nakano Satoshi, Naritaka Nakayuki, Minowa Kei, Sai Jin K, Shimizu Toshiaki
Abstract excerpt
OBJECTIVES: Causes of acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP) are sometimes difficult to determine in children. In such patients, genetic analysis may prove helpful. The present study analyzed mutations of cationic trypsinogen (PRSS1), serine protease inhibitor Kazal type 1 (SPINK1), chymotrypsin C (CTRC), and carboxypeptidase A1 (CPA1) and investigated the clinical features of children...
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