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The Membrane Attack Complex in Aging Human Choriocapillaris

7 Sept 2014

Abstract excerpt

Age-related macular degeneration (AMD) is a common disease that can result in severe visual impairment. Abnormal regulation of the complement system has been implicated in its pathogenesis, and CFH polymorphisms contribute substantially to risk. How these polymorphisms exert their effects is poorly understood. We performed enzyme-linked immunosorbent assay (ELISA) analysis on young, aged, and AMD choroids to...

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PMID: 25204844
DOI: 10.1016/j.ajpath.2014.07.017

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