Article
Is age-related macular degeneration a microvascular disease?
Advances in experimental medicine and biology - 1 Jan 2014
Mullins Robert F, Khanna Aditi, Schoo Desi P, Tucker Budd A, Sohn Elliott H, Drack Arlene V, Stone Edwin M
Abstract excerpt
Age-related macular degeneration (AMD) is a common, degenerative disease of the central retina affecting millions of elderly in the USA alone and many more worldwide. A better understanding of the pathophysiology of AMD will be essential for developing new treatments. In this review, we discuss the potential impact of complement complex deposition at the choriocapillaris of aging eyes and the relationship between...
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