Article

<i>G6PD</i> variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19

2020-06-02

Abstract excerpt

Chloroquine/hydroxychloroquine have been proposed as potential treatments for COVID-19. These drugs have warning labels for use in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Analysis of whole-genome sequence data of 458 individuals from sub-Saharan Africa showed significant G6PD variation across the continent. We identified nine variants, of which four are potentially deleterious to G6PD...

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Literature Corpus work: 32d1b68b-aa81-5def-8561-fe542b7c6994
DOI: 10.1101/2020.05.27.20114066

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