Article
Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice.
Nucleic acids research - 1 Jan 2014
Zhou Huanbin, Liu Bo, Weeks Donald P, Spalding Martin H, Yang Bing
Abstract excerpt
The Cas9/sgRNA of the CRISPR/Cas system has emerged as a robust technology for targeted gene editing in various organisms, including plants, where Cas9/sgRNA-mediated small deletions/insertions at single cleavage sites have been reported in transient and stable transformations, although genetic transmission of edits has been reported only in Arabidopsis and rice. Large chromosomal excision between two remote...
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