Article
Anorexia and impaired glucose metabolism in mice with hypothalamic ablation of Glut4 neurons.
Diabetes - 1 Feb 2015
Ren Hongxia, Lu Taylor Y, McGraw Timothy E, Accili Domenico
Abstract excerpt
The central nervous system (CNS) uses glucose independent of insulin. Nonetheless, insulin receptors and insulin-responsive glucose transporters (Glut4) often colocalize in neurons (Glut4 neurons) in anatomically and functionally distinct areas of the CNS. The apparent heterogeneity of Glut4 neurons has thus far thwarted attempts to understand their function. To answer this question, we used Cre-dependent,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.